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We hypothesize that organ culture induced inflammation could share some attributes with all the in vivo scenario following stroke, and hence evaluated U0126 and KN93, distinct inhibitors of MEK1/2 and of CaMKII, respectively, which have demonstrat read more...



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Moreover, FGF two enhanced microglial phagocytosis of neuronal debris induced by glutamate toxicity. We examined which variety of FGFR is involved in the FGF 2 induced phagocytosis, and observed that pan FGFR inhibitor PD173074 and read more...



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FGF 2 induced microglial neuroprotection through ERK MAPK and ERK activation is straight regulated by Wnt signaling To elucidate the signaling pathway of microglia mediated neuroprotection, we examined the impact of several kinase inhibitors on ne read more...



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FGFR1 to 4 were expressed in neurons and microglia. The expression of FGF 2 mRNA was detected in neurons and astrocytes. HIcotinib Glutamate or oAB enhances FGF two read more...